Office: O’Donoghue Research Building 333A

Lab: O’Donoghue Research Building 345

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Education:

• MSc in Clinical and Translational Science, University of Alabama at Birmingham, Birmingham AL (2019)
• Rheumatology Fellowship, Columbia University, New York, NY  (2010)
• Internal Medicine Residency, Cleveland Clinic Foundation, Cleveland, OH (2008)
• Doctor of Medicine, University of Sao Paulo, Brazil (2004)

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Research Interests:

• Effects of obesity on disease activity of patients with rheumatoid arthritis: mechanisms and nutritional interventions
• Physical impairment in rheumatoid arthritis and exercise interventions
• Skeletal muscle dysfunction
• Changes in body composition 
• Insulin resistance
• Cardiovascular disease
• Idiopathic inflammatory myopathies

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Select Publications:

• Moellering, D. R., Smith-Johnston, K., Kelley, C., Sammy, M. J., Benedict, J., Brock, G., Johnson, J., Baskin, K. K., Jarjour, W. N., Belury, M. A., Reiser, P. J., Nagareddy, P., Hanaoka, B. Y. (2023). Association between skeletal muscle mitochondrial dysfunction and insulin resistance in patients with rheumatoid arthritis: a case-control study. Arthritis research & therapy, 25(1), 85. PMID: 37210569. DOI: 10.1186/s13075-023-03065-z 
• Dragoljevic, D., Lee MKS, Pernes, G., Morgan, P. K., Louis, C., Shihata, W., Huynh, K., Kochetkova, A. A., Bell, P. W., Mellett, N. A., Meikle, P. J., Lancaster, G. I., Kraakman, M. J., Nagareddy, P., Hanaoka, B. Y., Wicks, I. P., Murphy, A. J. (2023). Administration of an LXR agonist promotes atherosclerotic lesion remodelling in murine inflammatory arthritis. Clinical & translational immunology, 12(4), e1446. PMID: 37091327. DOI: 10.1002/cti2.1446 
• Hanaoka, B. Y. (2022). Interaction effect of systemic inflammation and modifiable rheumatoid cachexia risk factors on resting energy expenditure in patients with rheumatoid arthritis. JCSM Clinical Reports. 
• Dragoljevic, D., Lee MKS, Louis, C., Shihata, W., Kraakman, M. J., Hansen, J., Masters, S. L., Hanaoka, B. Y., Nagareddy, P., Lancaster, G. I., Wicks, I. P., Murphy, A. J. (2020). Inhibition of interleukin-1β signalling promotes atherosclerotic lesion remodelling in mice with inflammatory arthritis. Clinical & translational immunology, 9(11), e1206. PMID: 33204425. DOI: 10.1002/cti2.1206 
• Coleman, K. J., Schlundt, D. G., Bonnet, K. R., Holmquist, K. J., Dunne, J., Crull, E., Hanaoka, B. Y., Lent, M. R., Nadglowski, J., Sylvia, L., Venkatachalam, S., Xanthakos, S. A., Zeiger, R., Arterburn, D., Williams, N., Courcoulas, A., Anau, J., McTigue, K. M., Blalock, C., Malanga, E., McClay, J., McBride, C. L., Schlundt, D., Emiliano, A., Nemr, R., McTigue, K., Courcoulas, A., Xanthakos, S. A., Michalsky, M., Coleman, K. J., Murali, S., Tavakkoli, A., Desai, N., Apovian, C., Clark, J., Nauman, E., Cirielli, E., Nadglowski, J., St Clair, T., Tice, J., Vitello, J., Zeiger, R., Arterburn, D., Anau, J., Janning, C., Williams, N. (2020). Understanding the Bariatric Patient Perspective in the National Patient-Centered Clinical Research Network (PCORnet) Bariatric Study. Obesity surgery, 30(5), 1837-1847. PMID: 31965490. DOI: 10.1007/s11695-020-04404-8 
• Sreejit, G., Abdel-Latif, A., Athmanathan, B., Annabathula, R., Dhyani, A., Noothi, S. K., Quaife-Ryan, G. A., Al-Sharea, A., Pernes, G., Dragoljevic, D., Lal, H., Schroder, K., Hanaoka, B. Y., Raman, C., Grant, M. B., Hudson, J. E., Smyth, S. S., Porrello, E. R., Murphy, A. J., Nagareddy, P. (2020). Neutrophil-Derived S100A8/A9 Amplify Granulopoiesis After Myocardial Infarction. Circulation, 141(13), 1080-1094. PMID: 31941367. DOI: 10.1161/CIRCULATIONAHA.119.043833 
• Dragoljevic, D., Kraakman, M. J., Nagareddy, P., Ngo, D., Shihata, W., Kammoun, H. L., Whillas, A., Lee MKS, Al-Sharea, A., Pernes, G., Flynn, M. C., Lancaster, G. I., Febbraio, M. A., Chin-Dusting, J., Hanaoka, B. Y., Wicks, I. P., Murphy, A. J. (2018). Defective cholesterol metabolism in haematopoietic stem cells promotes monocyte-driven atherosclerosis in rheumatoid arthritis. European heart journal, 39(23), 2158-2167. PMID: 29905812. DOI: 10.1093/eurheartj/ehy119 
• Hanaoka, B. Y., Ormseth, M. J., Michael Stein, C., Banerjee, D., Nikolova-Karakashian, M., Crofford, L. J. (2018). Secretory sphingomyelinase (S-SMase) activity is elevated in patients with rheumatoid arthritis. Clinical rheumatology, 37(5), 1395-1399. PMID: 28914380. DOI: 10.1007/s10067-017-3824-1 
• Hanaoka, B. Y., Cleary, L. C., Long, D. E., Srinivas, A., Jenkins, K. A., Bush, H. M., Starnes, C. P., Rutledge, M., Duan, J., Fan, Q., Fraser, N., Crofford, L. J. (2015). Physical impairment in patients with idiopathic inflammatory myopathies is associated with the American College of Rheumatology functional status measure. Clinical rheumatology, 34(11), 1929-37. PMID: 25388646. DOI: 10.1007/s10067-014-2821-x 
• Cleary, L. C., Crofford, L. J., Long, D., Charnigo, R., Clasey, J., Beaman, F., Jenkins, K. A., Fraser, N., Srinivas, A., Dhaon, N., Hanaoka, B. Y. (2015). Does computed tomography-based muscle density predict muscle function and health-related quality of life in patients with idiopathic inflammatory myopathies? Arthritis care & research, 67(7), 1031-40. PMID: 25623494. DOI: 10.1002/acr.22557

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