America's teachers are among the most overworked and underappreciated groups in our nation. Specifically, early childhood education (ECE) teachers face disparities that influence their health and well-being. Teachers are integral to educational systems, and their wellness impacts development of the children they teach. Moreover, physical and occupational therapists have leadership opportunities to, directly and indirectly, influence the wellness of students through their teachers. Our research team, the Happy Teacher Project, developed and tested a conceptual model using job demands and resources as frameworks to examine teacher wellness. The model demonstrated relationships between physical activities and sedentary behaviors, suggesting these modifiable risk factors can be addressed to improve the overall well-being of ECE teachers and by extension, their students. The purpose of the study, part of a four-year project, takes a holistic and multi-faceted approach (our research team consists of 11 researchers representing nine disciplines at OU and the OU Health Sciences Center) to promote ECE teacher well-being and improve working conditions.