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Faculty and Staff Directory

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Franklin Hays, PhD

  • Assistant Professor
  • Director, Laboratory of Redox Biology
  • Member, Harold Hamm Diabetes Center
  • Member, Data Institute for Societal Changes
  • Associate Member, Stephenson Cancer Center

AHB 3064 (office) and AHB 3051 (Laboratory)

(405)271-8001, ext. 41182

Franklin-Hays@ouhsc.edu


Education:

  • 2009 - 2010 Postdoctoral Scholar, Biochemistry and Molecular Biology, OUHSC, Oklahoma City, OK
    Research focus: Glycobiology and HA Synthase functional characterization
    Mentor: Paul H. Weigel, Ph.D. 
  • 2005 - 2009 NRSA/Sandler Postdoctoral Fellow, Biochemistry and Biophysics, UCSF, San Francisco, CA 
    Research focus: Integral membrane protein structure, function, and production 
    Mentor: Robert M. Stroud, Ph.D. 
  • 2000 - 2005 Doctor of Philosophy, Biochemistry and Biophysics, Oregon State University, Corvallis, OR 
    Dissertation: Sequence Dependent Conformational Variations in DNA Holliday Junctions 
    Committee: Pui Shing Ho, Ph.D. (Advisor); Joseph Beckman, Ph.D.; Andrew Karplus, Ph.D.; Tory Hagen, Ph.D.; Mike Schimerlik, Ph.D.; Ken van Holde, Ph.D. 
  • 1996 - 2000 Bachelor of Science, Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, OK 
    Senior Thesis: Direct Substrate Channeling in Glycolytic Dehydrogenases
    Advisor: H Olin Spivey, Ph.D. 


Teaching:

Undergraduate:

  • HES 2823: Introductory Nutrition, OU in Arezzo (Italy)

Graduate & Professional:

  • NS 5104: Nutritional Biochemistry and Physiology
  • NS 5823: Energy Nutrients
  • NS 5833: Non-Energy Nutrients

Graduate:

  • NS 5970: MS Seminar
  • AHS 6970: PhD Seminar
  • BMSC 5221: Interdisciplinary First Year Journal Club


Funding:

Recent funding, see CV for complete list

  • Hays, F. A. (PI), "Development of a Database on Nitrite and Nitrate in Foods and Dietary Supplements"  U.S. Department of Agriculture (USDA:NIH/ODS Interagency Agreement 60-8040-2-006), Federal
    June 1st, 2022 – May 31st, 2025 
  • Hays, F. A. (PI), Zhang, X. (Co-PI), "Tetraspanin CD8 Lipid-Dependent Structural Changes Involved in Inhibition of Tumor Cell Movement" Stephenson Cancer Center, CAH, & VPR Research Support, State
    July 1, 2023 - June 30, 2024 
  • Hays, F. A. (PI), "Deciphering ShcA-mediated ROS Production as a Novel Intervention Strategy in Diabetes Therapy" NIH R01, Sponsored by National Institutes of Health, Federal
    Grant/Contract Number: 1R01GM118599
    September 15, 2016 - July 31, 2021


Select Publications:

Select Publications, See CV or PubMed for a complete list:

  • Pinaffi-Langley A., Dajani, R.M., Prater M.C., Nguyen H.V., Vranken K., Beaver L., Hays F.A., and Hord N.G. (2023) “Dietary nitrate from plant foods: a conditionally essential nutrient for cardiovascular health”. Adv. Nutr. https://pubmed.ncbi.nlm.nih.gov/38008359/
  • Haslem, L., Hays, J. M., Schmitz, H., Matsuzaki, S., Sjoelund, V., Byrum, S. D., Humphries, K. D., Frazer, J. K., Demeler, B., Benbrook, D. M., Tierney, R. M., Duggan, K. D., and Hays, F. A. (2022) “p66Shc is an Apoptotic Rheostat Whose Targeted ROS Inhibition Improves MI Outcomes”. https://www.biorxiv.org/content/10.1101/2022.04.14.487897v1.full 
  • Haslem, L., Brown, M., Zhang, X.A., Hays, J.M. and Hays, F. A. (2022) "Purification of Membrane Proteins Overexpressed in Saccharomyces cerevisiae".  Methods Mol. Bio.; 2507:143-173; PMID:35773581 https://pubmed.ncbi.nlm.nih.gov/35773581/
  • Haslem, L., Hays, J.M. and Hays, F. A. (2022) "p66Shc in Cardiovascular Biology". Cells; June 6; 11(11):1855; PMID: 35681549
    https://pubmed.ncbi.nlm.nih.gov/35681549/